Myocardial Contrast Echocardiographic Diagnosis and Follow-Up of Interventricular Septal Hematoma after Retrograde Intervention for a Chronic Total Occlusion of a Right Coronary Artery: a Case Report.

Background:Chronic total occlusion percutaneous coronary interventions (CTO-PCI) can be highly complex and are associated with an increased risk of complications. Coronary perforation (CP) is one of the most feared complications of CTO-PCI. Awareness of the potential consequence, as well as meticulous attention to patient monitoring, can aid in rapid treatment if it happens. We present a unique case covering myocardial contrast echocardiography (MCE) characterization of interventricular septal hematoma secondary to CP associated with decompression of the hematoma into the left ventricle cavity and a favorable clinical outcome.Case Description:This is a case of a patient with no space-occupying effect in interventricular septum before CTO-PCI showed severe chest pain after PCI. Bedside echocardiography showed thickening of the interventricular septum with the anechoic area, and contrast-enhanced echocardiography suggested the presence of interventricular septal hematoma and coronary-ventricular fistula. It was considered that retrograde CTO-PCI led to CP, which developed into an interventricular septal hematoma. The hematoma obstructed the right ventricular outflow tract (RVOT) to a lesser amount; at the same time, the perforated coronary artery created a fistula with the left ventricle, resulting in perfusion damage and myocardial ischemia to some extent, although the patient's vital signs remained stable. Therefore, conservative treatment was carried out under close observation. The patient stayed stable. The hematoma was absorbed 7 days after the operation, and completely absorbed 1 month later.Conclusions:Although most cases of myocardial hematoma caused by CP can be treated conservatively without causing acute hemodynamic damage, a myocardial hematoma can progress at any time. Closely monitoring the changes in patients' symptoms and vital signs; mastering the location of the perforated coronary artery, the size of the hematoma and the hemodynamic abnormalities can help clinicians quickly make further treatment plans. Echocardiography coupled with contrast-enhanced ultrasonography, which is non-invasive, safe, cost-effective, and bedside-operable may accurately indicate the location, size of the hematoma, whether there is a shunt, as well as observe the hemodynamic changes and myocardial perfusion in real-time.