FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment?
Cell Reports Medicine(2022)
摘要
FGF21 is a liver-derived hormone primarily involved in glucose/lipid metabolism. A recent study by Flippo and colleagues(1) demonstrates that administration of FGF21 or an FGF21 analog suppresses alcohol consumption in rodents and non-human primates, likely through an amygdalo-striatal circuit.
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