BNT162B2 COVID-19 mRNA vaccination did not promote substantial anti-syncytin-1 antibody production nor mRNA transfer to breast milk in an exploratory pilot study

Citra N Z Mattar,Winston Koh,Yiqi Seow,Shawn Hoon, Aparna Venkatesh,Pradip Dashraath, Li Min Lim,Judith Ong, Rachel Lee,Nuryanti Johana,Julie S L Yeo, David Chong,Lay Kok Tan,Jerry K Y Chan,Mahesh Choolani,Paul Anantharajah Tambyah

ANNALS ACADEMY OF MEDICINE SINGAPORE（2022）

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摘要

Dear Editor, Vaccine hesitancy still threatens global efforts to end the COVID-19 pandemic caused by SARS-CoV-2 and its emerging variants. Social media-driven “conspiracy theories” cast doubts on vaccine safety for reproductive health,1 including concerns that vaccine-induced SARS-CoV-2-neutralising antibodies (NAb) cross-react with human syncytin-1—a protein involved in gamete fertilisation and normal placental development2—resulting in infertility or

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vaccination,breast milk,antibody,mrna transfer,anti-syncytin

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