Comparison of performance of varicella vaccines via infectious disease modeling

Matthew Pillsbury,Cristina Carias,Salome Samant,David Greenberg,Manjiri Pawaskar

Vaccine（2022）

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摘要

•We developed a new deterministic compartmental model for varicella vaccination.•This model fits 10-year clinical trial data for both V-MSD and V-GSK.•This model allows the direct comparison of performance of varicella vaccines.•90% were permanently protected with the first dose of V-MSD versus 62% with V-GSK.•97% were permanently protected with two doses of V-MSD compared to 94% with V-GSK.

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关键词

Varicella,Prevention and control,Epidemiology,Varicella vaccine,Immunization programs,Vaccination models

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