Feasibility of biology-guided radiotherapy using PSMA-PET to boost to dominant intraprostatic tumour

Mathieu Gaudreault,David Chang,Nicholas Hardcastle,Price Jackson,Tomas Kron,Michael S. Hofman,Shankar Siva

Clinical and Translational Radiation Oncology（2022）

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摘要

•Biology-guided radiation therapy (BGRT) uses PET imaging for online image guidance.•PSMA PET uptake is abundant in the dominant intraprostatic lesion (DIL).•BgRT boost to PSMA-avid subvolume in the prostate region may be feasible.•Suitable targets for BgRT were identified in the ProPSMA clinical trial.

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关键词

BgRT,PSMA,DIL,Prostate,BTZ

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