Effects of Menstrual Cycle on Various Morphologies of High-Grade Squamous Intraepithelial Lesions in SurePath™ Liquid-Based Cervical Cytology.

Mitsuaki Okodo,Kaori Okayama,Natsuko Tsukakoshi,Yukimi Misawa,Kazumasa Tanabe,Koji Teruya,Chieko Ito,Yasuyoshi Ishii,Masahiko Fujii,Mizue Oda

Acta cytologica（2022）

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摘要

The present study demonstrated that HSIL cells in Pap smears in the late proliferation phase have a high frequency of single-cell-like patterns. In human papillomavirus-positive Pap smears with a clean background and predominantly superficial cells, careful microscopic observation by targeting single HSIL cells can potentially reduce false negatives.

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关键词

Cervical intraepithelial neoplasia,False negative,High-grade squamous intraepithelial lesion,Liquid-based cytology,Single cell

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