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BMP4 Regulates EMT to be Involved in non-Syndromic Cleft lip With or Without Palate.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association(2022)

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摘要
BMP4 enhances cell migration and promotes cell EMT through Smad1 signaling pathway. Abnormal BMP4 mediates migration and EMT through other relevant signaling pathways resulting in NSCL/P. The study provides new insight into the mechanisms of NSCL/P associated with BMP4.n.
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关键词
bone morphogenetic protein 4,bone morphogenetic protein 4/Smad1 signaling pathway,epithelial–mesenchymal transition,non-syndromic cleft lip with or without palate
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