The Phosphatidyl- myo -Inositol Dimannoside Acyltransferase PatA Is Essential for Mycobacterium tuberculosis Growth In Vitro and In Vivo

Francesca Boldrin,Itxaso Anso,Sogol Alebouyeh,Iker A. Sevilla,Mariví Geijo,Joseba M. Garrido,Alberto Marina,Laura Cioetto Mazzabò,Greta Segafreddo,Marcelo E. Guerin,Riccardo Manganelli,Rafael Prados-Rosales

Journal of Bacteriology（2021）

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摘要

Tuberculosis (TB) is the leading cause of death from a single infectious agent. The emergence of drug resistance in strains of M. tuberculosis , the etiologic agent of TB, emphasizes the need to identify new targets and antimicrobial agents.

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