Longitudinal in-vivo quantification of tumour microvasculature heterogeneity via optical coherence tomography (OCT) angiography in a pre-clinical model of radiation therapy

Nader Allam,W. Jeffrey Zabel,Blake Jones,Valentin Demidov,Edward Taylor,I. Alex Vitkin

Optical Coherence Imaging Techniques and Imaging in Scattering Media IV（2021）

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摘要

Stereotactic body radiotherapy’s radiobiological mechanism of action is unknown, impeding development of adaptive irradiation schedules. A new vascular biomarker with predictive potential of tumour radiation response and hypoxia is extracted via OCT angiography longitudinally.

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