Melt-Electrowritten Poly(L-lactic acid)- and Bioglass-Reinforced biomimetic hydrogel for bone regeneration

Jie Meng,Francesco Boschetto,Shinichi Yagi,Elia Marin,Tetsuya Adachi,Xuefei Chen,Giuseppe Pezzotti,Shinichi Sakurai,Hideki Yamane,Huaizhong Xu

Materials & Design（2022）

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摘要

•Biomimetic melt electrowritten lattice and bioglass particle reinforced hydrogel scaffolds were first fabricated.•The mechanism of the reinforcement and in vitro behavior of the composite scaffold were studied.•The optimized scaffold possessed both high modulus and elevated in vitro osteoinduction/conduction capability.

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关键词

Melt electrospinning writing,Hydrogel,Bioglass,Scaffold,Mechanical property,Bone regeneration

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