Evidence of co-infections during Delta and Omicron SARS-CoV-2 variants co-circulation through prospective screening and sequencing.

Patricia Combes,Maxime Bisseux,Antonin Bal, Pierre Marin,Justine Latour,Christine Archimbaud,Amélie Brebion,Hélène Chabrolles,Christel Regagnon,Jérémy Lafolie,Gregory Destras,Bruno Simon,Jacques Izopet,Laurence Josset,Cécile Henquell,Audrey Mirand

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases（2022）

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摘要

This work demonstrates that SARS-CoV-2 Delta/Omicron co-infections are not rare in high virus co-circulation periods. Moreover, co-infections can further lead to genetic recombination which may generate new chimeric variants with unpredictable epidemic or pathogenic properties that could represent a serious health threat.

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关键词

Delta and Omicron VOC,Recombination,SARS-CoV-2 co-infection,Single nucleotide polymorphism screening,Whole genome sequencing

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