Both Disease Activity and HLA-B27 Status Are Associated With Gut Microbiome Dysbiosis in Spondyloarthritis Patients.

Magali Berland,Victoria Meslier,Samar Berreira Ibraim,Emmanuelle Le Chatelier,Nicolas Pons,Nicolas Maziers,Florence Thirion,Franck Gauthier,Florian Plaza Oñate,Jean-Pierre Furet,Ariane Leboime,Roula Said-Nahal,Florence Levenez,Nathalie Galleron,Benoît Quinquis,Philippe Langella,Stanislav Dusko Ehrlich,Maxime Breban

Arthritis & rheumatology (Hoboken, N.J.)（2023）

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摘要

These findings reveal that genetic background and level of disease activity are likely to influence the composition of the gut microbiota of patients with SpA. It may be appropriate for further research on chronic arthritis to focus on these key parameters.

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