T-cell immune response predicts the risk of critical SARS-Cov2 infection in hospitalized COVID-19 patients

Maxime Samson,Barbara Nicolas,Marion Ciudad,Hélène Greigert,Alexandre Guilhem,Claudie Cladiere, Cécile Straub,Mathieu Blot,Lionel Piroth,Thomas Rogier,Hervé Devilliers,Patrick Manckoundia,Thibault Ghesquiere,Stéphanie Francois,Daniela Lakomy,Sylvain Audia,Bernard Bonnotte

European Journal of Internal Medicine（2022）

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摘要

•Th17 cells are increased in patients who progress to critical Covid-19.•In severe Covid-19, Th17>0.435% of CD4 t cells is associated with poorer survival.Assessment of Th17 cells could help target patients in need of anti-IL6R therapy.

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SARS Cov2,Covid-19,Th17 cells,IL-6

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