Investigating VEGF. miR-145-3p, and miR-101-3p Expression in Patients with Cholangiocarcinoma.

Maria Clara Jessica Calastri,Rafael Fernandes Ferreira,Graciele Domitila Tenani, Lucas Poleto Spinola, Gabriel Feltrin Vieira,Maria Filomena Rabaça Roque Botelho,Ana Margarida Coelho Abrantes,José Guilherme Lopes Rodrigues Tralhão,Ana Filipa Marques De Brito,Renato Ferreira Da Silva,Rita De Cassia Martins Alves Da Silva, Eliane Milharcix Zanovelo,Larissa Bastos Eloy Da Costa, Daniele Caroline Brito De Souza, Dalisio De Santi Neto,Ilka De Fatima Santana Ferreira Boin,Doroteia Rossi Silva Souza

Asian Pacific journal of cancer prevention : APJCP（2022）

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摘要

The underexpression of miRNAs, tumor suppressors, the overexpression of VEGF, smoking, and aging were associated with CCA based on our findings. It seems that the reduced expression of the studies miRNAs and increased expression of VEGF can contribute to a decrease in survival rate of patients with tumor in their intrahepatic bile ducts.

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Bile Duct Diseases,Gene expression,MicroRNAs,Molecular biology

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