Pathobiology of the Klotho Antiaging Protein and Therapeutic Considerations.
Frontiers in aging(2022)
摘要
The α-Klotho protein (henceforth denoted Klotho) has antiaging properties, as first observed in mice homozygous for a hypomorphic
Klothokl/kl
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关键词
FGF23,IGF-1,NF-KappaB,TGF-beta,Wnt,aging,hyperphosphatemia,klotho
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