The influence of modifiable cardiovascular risk factors on cognition, functioning, and inflammatory markers in first-episode psychosis: Results from a 2-year follow-up study

•First Episode Psychosis patients with two or more cardiovascular risk factors showed a slower performance on the TMT-A test.•First Episode Psychosis patients with two or more cardiovascular risk factors showed higher lymphocyte levels.•No longitudinal changes were observed in cognitive nor white blood cell markers at 2-year follow-up.•Our findings suggest the importance of targeting both cardiovascular risk factors and cognitive deficits in first-episode psychosis.•Compared with First Episode Psychosis patients with zero or one cardiovascular risk factors.