Multi-layered ZIF-coated Cells for the Release of Bioactive Molecules in Hostile Environments
Chemical communications(2022)
摘要
Metal-organic framework (MOF) coatings on cells enhance viability in cytotoxic environments. Here, we show how protective multi-layered MOF bio-composite shells on a model cell system (yeast) enhance the proliferation of living cells exposed to hostile protease-rich environments via the dissolution of the shells and release of a protease inhibitor (antitrypsin).
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