In vivo 2-Hydroxyglutarate Monitoring With Edited MR Spectroscopy for the Follow-up of IDH-Mutant Diffuse Gliomas: The IDASPE Prospective Study.

EUROPEAN JOURNAL OF NEUROLOGY（2022）

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摘要

MEGA-PRESS edited MRS allows monitoring of 2-hydroxyglutarate, confirming efficacy of inhibition and suggests different patterns of tumor progression in astrocytomas compared to oligodendrogliomas.

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关键词

2-hydroxyglutarate (2HG),IDH1/2 mutations,diffuse gliomas,edited MR spectroscopy,noninvasive detection

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