Use of SBA-15 mesoporous silica and colloidal silica as terfenadine adsorbents. A comparative study
PRZEMYSL CHEMICZNY(2022)
摘要
Terfenadine was adsorbed from its solns. in MeCN on a SBA-15 and Aerosil SiO2. Nonlinear fitting anal. was used to estimate the parameters of the Freundlich, Langmuir, Jovanovic, Dubinin-Astakhov and Redlich-Peterson isotherms. The max. adsorption capacity was 160.4 mg/g and 85.7 mg/g (Dubinin-Astakhov model) for SBA-15 and Aerosil silicas resp. It was shown that phys. adsorption was the main force of drug-SiO2 surface interactions.
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关键词
silica, drug adsorption, drug delivery system, adsorption isotherms
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