Impact of Medication Nonadherence in a Clinical Trial of Dual Antiplatelet Therapy

Marco Valgimigli,Enrico Frigoli,Pascal Vranckx,Yukio Ozaki,Marie-Claude Morice,Bernard Chevalier,Yoshinobu Onuma,Stephan Windecker, Laurent Delorme,Petr Kala,Sasko Kedev,Rajpal K. Abhaichand,Vasil Velchev,Willem Dewilde,Jakub Podolec,Gregor Leibundgut, Dragan Topic,Carl Schultz,Goran Stankovic,Astin Lee

Journal of the American College of Cardiology（2022）

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摘要

In the MASTER DAPT adherent population, 1-month compared with ≥3-month DAPT was associated with similar NACE or MACE and lower MCB. Among OAC patients, SAPT discontinuation after 6 months was associated with similar MACE and lower MCB than SAPT continuation (Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With an Abbreviated Versus Prolonged DAPT Regimen [MASTER DAPT]; NCT03023020).

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关键词

acetylsalicylic acid,drug-eluting stent,dual antiplatelet therapy,high bleeding risk,P2Y12 inhibitor

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