Combination Therapy of Chemotherapy or Radiotherapy and the Neurokinin-1 Receptor Antagonist Aprepitant: A New Antitumor Strategy?

Prema Robinson,Rafael Coveñas,Miguel Muñoz

Current medicinal chemistry（2023）

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摘要

This combination strategy once confirmed, might open the door to a new era in chemotherapy and radiotherapy with greater antitumor activity and fewer side effects. This treatment strategy could possibly translate into higher cure rates, better quality of life and fewer sequelae in cancer patients.

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关键词

Aprepitant,NK-1 receptor antagonist,antitumor,cancer,chemotherapy,combination therapy,radiotherapy,substance P

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