Solitary fibrous tumor of the tongue: a case report

Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm originally described in pleura with rare presentation in oral cavity. Herein, we showed a case of a 28-year-old male patient who presented an asymptomatic slow-growing mass in the anterior part of the tongue. Intraoral examination revealed a well circumscribed mass covered by normal mucosa with fibrous consistency. Due to nonspecific clinical findings, the initial diagnostic hypotheses include several submucosal neoplasms such as leiomyoma, neurofibroma, and others. An excisional biopsy was performed. Microscopically, the tumor was surrounded by a thick fibrous capsule, and hypo- and hypercellular areas were arranged in a storiform pattern with a stroma formed by collagen and abundant vascularization. Tumor cells showed immunopositivity for CD34 and CD99, and no expression of AML, S-100, or Ki-67. According to these findings, the diagnosis of STF was established. Although oral involvement is rare, STF should be included in the differential diagnosis of submucosal oral lesions. Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm originally described in pleura with rare presentation in oral cavity. Herein, we showed a case of a 28-year-old male patient who presented an asymptomatic slow-growing mass in the anterior part of the tongue. Intraoral examination revealed a well circumscribed mass covered by normal mucosa with fibrous consistency. Due to nonspecific clinical findings, the initial diagnostic hypotheses include several submucosal neoplasms such as leiomyoma, neurofibroma, and others. An excisional biopsy was performed. Microscopically, the tumor was surrounded by a thick fibrous capsule, and hypo- and hypercellular areas were arranged in a storiform pattern with a stroma formed by collagen and abundant vascularization. Tumor cells showed immunopositivity for CD34 and CD99, and no expression of AML, S-100, or Ki-67. According to these findings, the diagnosis of STF was established. Although oral involvement is rare, STF should be included in the differential diagnosis of submucosal oral lesions.