Tim3scFv-Transforming Lactobacillus Inhibits Transplanted Tumor of Renal-Cell Carcinoma.

Zerong Chen,Haibo Zhang,Jialiang Hui,Yaodong Jiang,Zehai Huang,Zhuangfei Chen,Weisen Zeng

Urologia internationalis（2023）

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摘要

Secretion of CTB-Tim3scFv promoted the proliferation and activation of spleen lymphocytes and inhibited growth, cell proliferation, and angiogenesis of tumors. The proposed method is low cost and convenient with potential to become a new immunotherapy approach for renal-cell carcinoma.

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关键词

Gene transformation,Immune checkpoint blockers,Lactococcus lactis,Renal-cell carcinoma,Tim3scFv

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