Genomic Characterization of SARS-CoV-2 from Vaccine Breakthrough Cases in Allegheny County, Pennsylvania

Kady D. Waggle,Marissa P. Griffith,Lei Zhu,Vaughn S. Cooper,Daniel J. Snyder,Vatsala Srinivasa,Tung Phan,Alan Wells,Graham M. Snyder,Daria Van Tyne,Lee H. Harrison,Jane W. Marsh

PloS one（2022）

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摘要

We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses of SARS-CoV-2 to vaccination.

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