Variability in Serum Concentrations and Clinical Response in Artisanal Versus Pharmaceutical Cannabidiol Treatment of Pediatric Pharmacoresistant Epilepsy.
The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG（2022）
摘要
Pharmaceutical-CBD achieves higher serum CBD concentrations than artisanal-CBD in pediatric patients with refractory epilepsy. These higher CBD concentrations are associated with increased reported adverse effects, but no detectable difference in seizure frequency.
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关键词
Dravet syndrome,Epidiolex,Lennox-Gastaut syndrome,artisanal cannabidiol,cannabidiol,pediatric epilepsy
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