Catheter-directed Thrombolysis for Acute SVC Obstruction in a Patient with Metastatic Breast Cancer

We report a case of acute port-a-cath associated superior vena caval thrombosis in a longstanding, previously uncomplicated vascular access device in a patient with stable ER+/PR+/HER2+ metastatic breast cancer. There was limited clinical improvement following initial treatment with subcutaneous low molecular weight heparin (LMWH). Following multidisciplinary team discussion, it was decided to proceed with catheter-directed thrombolysis, which resulted in complete symptom resolution.