Possible metabolic interplay between quality of life and fecal microbiota in a presenior population: Preliminary results

•Gut microbiota diversity is associated with different quality-of-life scores.•Increased fecal Actinobacteria abundance is linked to higher quality of life.•Decreased gut Peptostreptococcaceae abundance is related to enhanced quality of life.•Actinobacteria and Peptostreptococcaceae have been found to be related with mental health.