Betulinic acid improves TNF- α -induced insulin resistance by inhibiting negative regulator of insulin signalling and inflammation-activated protein kinase in 3T3-L1 adipocytes.
Archives of physiology and biochemistry(2022)
摘要
These results suggest that betulinic acid is effective at improving TNF--induced insulin resistance in adipocytes via inhibiting the activation of negative regulator of insulin signalling and inflammation-activated protein kinase and may potentially improve insulin resistance.
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关键词
Betulinic acid,IRS-1,JNK,PTP1B,insulin resistance
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