Critical Role of LMCD1 in Promoting Profibrotic Characteristics of Lung Myofibroblasts in Experimental and Scleroderma-Associated Lung Fibrosis.

Galina S Bogatkevich,Ilia Atanelishvili, Andrew M Bogatkevich,Richard M Silver

Arthritis & rheumatology (Hoboken, N.J.)（2023）

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摘要

Our study identifies LMCD1 as a profibrotic molecule contributing to the activation of myofibroblasts and the persistent fibroproliferation observed in SSc-ILD. Thus, LMCD1 may be a potential novel therapeutic target for patients with SSc-ILD.

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lung myofibroblasts

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