The role of multiple anatomical scenarios in plan optimization for carbon ion radiotherapy of pancreatic cancer

Silvia Molinelli,Alessandro Vai,Stefania Russo,Pierre Loap,Giorgia Meschini,Chiara Paganelli,Amelia Barcellini,Viviana Vitolo,Ester Orlandi,Mario Ciocca

Radiotherapy and Oncology（2022）

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摘要

•Planning on multiple anatomic scenarios could improve CIRT robustness for pancreatic cancer.•The PRV approach fails in predicting duodenum position along the RT course.•Efficient online adaptation is needed to guarantee CIRT quality for pancreatic cancer.

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关键词

Carbon ion radiotherapy,Pancreatic cancer,Robust optimization,Treatment adaptation

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