Immunomodulatory effects of carbon ion radiotherapy in patients with localized prostate cancer.

Wei Hu,Yulei Pei,Renli Ning,Ping Li,Zhenshan Zhang,Zhengshan Hong,Cihang Bao,Xiaomao Guo,Yun Sun,Qing Zhang

Journal of cancer research and clinical oncology（2022）

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摘要

CIRT demonstrates the potential to elicit immune activation in localized prostate cancer patients, based on sparing lymphocytes, increased lymphocyte proliferation, enhanced T-cell functionality, together with limited induction of immunosuppressive cells and reduced expression of immunosuppressive cytokines.

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关键词

Carbon ion radiotherapy,Immune response,Immunomodulatory effect,Peripheral immune cells,Prostate cancer

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