Asebogenin suppresses thrombus formation via inhibition of Syk phosphorylation.

Li Li,Xulin Xu,Keyu Lv,Guijuan Zheng,Hao Wang,Shuai Chen,Lang Huang,Yi Liu, Yadong Zhang,Zhaoming Tang,Lili Zhang, Jinyu Wang,Jianlin Qiao,Hongliang Li,Xuanbin Wang,Guangmin Yao,Chao Fang

British journal of pharmacology（2023）

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摘要

Asebogenin exhibits potent antithrombotic effects by targeting Syk and is a potential lead compound for the development of efficient and safe antithrombotic agents.

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关键词

asebogenin,neutrophil extracellular traps,platelet activation,spleen tyrosine kinase,thrombus formation

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