Sleep Disturbance, Irritability, and Response to Lurasidone Treatment in Children and Adolescents with Bipolar Depression

Manpreet K Singh,Cynthia Siu,Michael Tocco,Andrei Pikalov,Antony Loebel

Current neuropharmacology（2022）

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摘要

Our findings suggest that sleep disturbance and irritability are cardinal symptoms that “bridge” between depressive and manic symptom clusters and influence treatment outcomes in youth with bipolar depression.

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关键词

bridge symptoms,depression,hypomania,lurasidone,mixed mood,network analysis

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