HPLC-DAD-ESI-MS profile, antibacterial activity, and modulation of the activity of antibiotics by Carica papaya L. against Escherichia coli serotypes

Cícera Natalia Figueiredo Leite Gondim,Denise Aline Casimiro Bezerra,Nadghia Figueiredo Leite Sampaio, Maria Anésia Sousa de.Alencar,Roger Henrique Sousa da.Costa,Lucas Silva Abreu,Joanda Paolla Raimundo.e.Silva,Francisco Nascimento Pereira Junior,Josean Fechine Tavares,Marcelo Sobral da Silva,Jaime Ribeiro-Filho,Henrique Douglas Melo Coutinho

Phytomedicine Plus（2022）

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摘要

•The extract of C. papaya showed no clinically relevant antimicrobial action.•The extract did not modulates the antibiotic activity.•The HPLC-DAD-ESIMS analysis detected the presence of 17 compounds.

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关键词

Carica papaya,HPLC-DAD-ESI-MS,Antibacterial activity,Antibiotic resistance,E․ coli

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