Utility of a three-gene transcriptomic signature in the diagnosis of tuberculosis in a low-endemic hospital setting

Bih Hycenta Chendi,Tracey Jooste,Thomas Jens Scriba,Martin Kidd,Simon Mendelsohn,Kristian Tonby,Gerhard Walzl,Anne M. Dyrhol-Riise,Novel Njweipi Chegou

Infectious Diseases（2022）

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摘要

The three-genes signature may have potential to improve diagnosis of TB in a hospitalised low-burden setting. However, the influence of confounding variables or covariates such as age requires further evaluation in larger studies.

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关键词

Tuberculosis,biomarker,diagnosis,qPCR,transcriptomic signatures

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