An integrated fecal microbiome and metabolome in rats reveal variations in gut microbiota and fecal metabolic phenotype of Semen Euphorbiae and Semen Euphorbiae Pulveratum

Xiaotong Wei,Menglin Wang,Shuanghui Shi,Mingrui Jiang,Zhicheng Wang,Jingqiu Zhang,Zhuzhu Yue,Huinan Wang,Mengyu Chen,Yingzi Wang

Journal of Chromatography B（2022）

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摘要

•Semen Euphorbiae can reduce toxicity by frosting.•17 different metabolites before and after frosting were identified.•Analysis of fecal microbiota and metabolites by 16S rDNA and UPLC-Q-TOF-MS.

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关键词

Semen Euphorbiae,Gut microbiota,Metabolomics,16S rDNA sequencing,UPLC-Q-TOF/MS

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