DMAP and HMTA Manganese(iii) Meso-Tetraphenylporphyrin-based Coordination Complexes: Syntheses, Physicochemical Properties, Structural and Biological Activities

The reactions of the (triflato)(meso-tetra(para-methoxyphenyl)porphyrinato)manganese(III) ([MnIII(TMPP) (SO3CF3)] complex with an excess of 4-dimethylaminopyridine (DMAP) and hexamethylenetetramine (HMTA) have been examined. These reactions yield crystalline [MnIII(TMPP)(DMAP)2](0.1Cl)(0.9SO3CF3)center dot 2CHCl3 (I) and [MnIII(TMPP)(HMTA)2](SO3CF3)center dot 2CH2Cl2 (II) complexes, respectively. The hyper d-type electronic spectra of I-II are characteristic for high-spin (S = 2) Mn(III) metalloporphyrins with very redshifted Soret bands. A cyclic voltammetry investigation was carried out on these two Mn(III) coordination compounds. The crystal structures of the solid complexes I-II were determined by X-ray single-crystal diffraction and elucidated by Hirshfeld surface approach. Furthermore, bioactivity of the H2TMPP free base, the [MnIII(TMPP)(SO3CF3)] starting ma-terial and complexes I-II, was assessed by a set of in vitro tests checking for antioxidant, antibacterial and antifungal (against several strains) effects.