Physical Functional Impairment and the Risk of Incident Mild Cognitive Impairment in an Observational Study of World Trade Center Responders.

Alison Pellecchia,Minos Kritikos,Jack Guralnik,Isaac Ahuvia,Stephanie Santiago-Michels,Melissa Carr,Roman Kotov,Evelyn J Bromet,Sean A P Clouston,Benjamin J Luft

Neurology. Clinical practice（2022）

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摘要

WTC responders with PFI demonstrated worse cognitive and behavioral outcomes, and PFI played an intermediary role in the relationship between PTSD and incident MCI, suggesting that PFI may be an early indicator of MCI in responders with PTSD. Regular monitoring of PFI should be considered among PTSD populations.

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