Can amantadine cause resistant hypernatremia in the treatment of hypoxic brain injury due to cardiac arrest?
Turkish Journal of Nephrology(2022)
摘要
Out-of-hospital cardiac arrest complicated by neurological deterioration leads to a worse prognosis. Therapeutic hypothermia is the primary treatment to indicate utility in improving survival as well as limiting neurological damage in cardiac arrest patients. A 56-year-old male patient, not to be treated with therapeutic hypothermia, received more than 45 minutes of cardiopulmonary resuscitation but had significant damage as a result of hypoxic brain injury. We present a case of treatment-resistant hypernatremia, which was thought to be due to a neuroprotective agent used in hypoxic brain injury treatment and was not previously mentioned in the literature.
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关键词
Amantadine, cardiac arrest, hypernatremia, hypoxic brain injury
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