Soy-based diet and creatine supplementation: effects on cell signaling and doxorubicin response in the rat heart

A graded Fe based composite reinforced with tetragonal yttria stabilized zirconia, monoclinic zirconia, wüstite and at a less extent, Zr0.978Fe0.022O1.978 (tetragonal) and Zr0.85Y0.15O1.93 (cubic) was developed by high energy ball milling, compaction and sintering. Solid state sintering entailed (i) the growth of Fe grains which remained submicrometric and (ii) the coarsening of oxides reinforcements forming an interconnected network in the bulk graded composite.The increase of oxide reinforcements volume fraction enabled to obtain a material with a graded electrical resistivity and a slightly graded hardness; the bending resistance of the as-developed material was however decreased because of the weakness of the reinforcements – matrix bonds.