Barrett’s Esophagus and Esophageal Adenocarcinoma: A Histopathological Perspective
Thoracic Surgery Clinics(2022)
摘要
Esophageal adenocarcinoma (EAC) is increasing in prevalence. Barrett's esophagus (BE) has long been recognized as the putative precursor lesion for EAC, but much is still unknown regarding its cell of origin and what molecular factors influence its neoplastic progression. Accurate pathologic assessment of BE biopsies is important for identifying patients most at risk of progressing to EAC, whereas pathologic assessment of EAC specimens plays a major role in influencing therapeutic decision-making.
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关键词
Barrett’s esophagus,Esophageal adenocarcinoma,Regression grading,Molecular pathogenesis
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