Loss of Corneal Nerves and Corneal Haze in Patients with Fuchs’ Endothelial Corneal Dystrophy with the Transcription Factor 4 Gene Trinucleotide Repeat Expansion

Matthew Gillings, Andrew Mastro,Xunzhi Zhang, Kelly Kiser,Jane Gu,Chao Xing,Danielle M Robertson,W Matthew Petroll,V Vinod Mootha

Ophthalmology Science（2023）

引用 1|浏览14

暂无评分

摘要

Loss of corneal nerves in FECD supports the classification of the trinucleotide repeat expansion disorder as a neurodegenerative disease. Haze in the anterior, central, and posterior cornea correlate with severity, irrespective of the genotype. Quantitative assessments of corneal nerves and corneal haze may be useful to gauge and monitor FECD disease severity in RE+ patients.

查看译文

关键词

Confocal,Cornea,Fuchs’ endothelial corneal dystrophy,Imaging,Scheimpflug

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要