Haploidentical Hematopoietic Cell Transplantation for Myelofibrosis in the Ruxolitinib Era

In patients with myelofibrosis, haploidentical bone marrow transplantation following double-alkylating conditioning is associated with favorable rates of graft-versus-host disease and relapse.Graft failure is the major determinant of nonrelapse mortality and overall survival.Splenectomy is associated with a favorable rate of engraftment and is predictive of a higher risk of relapse.