Evaluation of standard versus reduced dose apixaban for the treatment of venous thromboembolism in patients with severe renal disease (ESRD-VTE)

Parker Knueppel, Seo Hyoun Bang, Camille Troyer,Alyssa Barriga,Jaekyu Shin,Christine L. Cadiz, Connie Abdo, Taylor McCart, Brittany Huynh,Craig Stevens,Crystal Zhou,Nuen Tsang Yang,Machelle Wilson, Tiffany Pon

Thrombosis Research（2022）

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摘要

•Optimal apixaban dosing for VTE in severe renal disease is currently debated.•Rates of bleeding and VTE were compared between standard vs reduced dose apixaban.•Clinically relevant bleed rate was significantly lower with reduced dose apixaban.

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关键词

Anticoagulation,Apixaban,Renal disease,Venous thromboembolism,dialysis

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