Hypoxic storage of donor red cells preserves deformability after exposure to plasma from adults with sickle cell disease.

Matthew S Karafin,Joshua J Field,Anton Ilich, Lang Li, Bahjat F Qaquish,Sergey S Shevkoplyas,Tatsuro Yoshida

Transfusion（2023）

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摘要

Hypoxic storage significantly influenced RBC deformability. Patient condition significantly influenced post-incubation hemolysis. Together, HRBCs in steady-state plasma maximized donor red cell ex vivo function and survival.

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关键词

red blood cells,sickle cell disease,storage lesion

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