The double-sided of human leukocyte antigen-G molecules in type 1 autoimmune hepatitis.

Frontiers in immunology（2022）

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摘要

This study highlights the positive immunomodulatory effect of HLA-G molecules on the clinical course of AIH-1 and how this improvement closely correlates with plasma levels of sHLA-G. However, our results open the debate on the ambiguous role of HLA-G molecules expressed by plasma cells, which are pathognomonic features of AIH-1.

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关键词

HLA-G 3’UTR haplotypes,HLA-G alleles,Sardinian population,anti-HLA-G monoclonal antibodies,human leukocyte antigen,plasma cell,soluble HLA-G,type 1 autoimmune hepatitis

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