Predicting radiotherapy-induced xerostomia in head and neck cancer patients using day-to-day kinetics of radiomics features

Thomas Berger,David J. Noble,Leila E.A. Shelley,Thomas McMullan,Amy Bates,Simon Thomas,Linda J. Carruthers,George Beckett,Aileen Duffton,Claire Paterson,Raj Jena,Duncan B. McLaren,Neil G. Burnet,William H. Nailon

Physics and Imaging in Radiation Oncology（2022）

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摘要

•Textural features on daily images outperformed dose/volume parameters.•The best models could be used before or at mid-treatment for personalisation.•Area under the curve of the best models at 6, 12 and 24 months was 0.69, 0.74 and 0.86.

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关键词

Head and neck cancer,Radiomics,Xerostomia,Parotid gland,Mega-voltage CT

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