N(Omega)-nitro-l-arginine methyl ester potentiates lidocaine analgesic and anaesthetic effect in rats.

The Journal of pharmacy and pharmacology（2023）

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摘要

L-NAME at 60 nmol (the minimum effective dose) increases and prolongs the effect of cutaneous analgesia of lidocaine. L-NANE at an ineffective dose potentiates lidocaine analgesic and anaesthetic effects.

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N(Omega)-nitro-l-arginine methyl ester,infiltrative cutaneous analgesia,lidocaine,spinal block

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