Outcomes of keratolimbal allograft from ABO compatible donors for severe bilateral limbal stem cell deficiency

Michael Mimouni,Edward Cole,S Joseph Kim,Jeffrey Schiff, Carl Cardella,Kathryn J Tinckam,Allan R Slomovic,Clara C Chan

The Ocular Surface（2023）

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摘要

Preliminary outcomes of KLAL with ABO compatible tissue using the Cincinnati protocol, preoperative basiliximab (when PRA present) and post-operative IVIG (when DSA present) are encouraging. This protocol may allow for utilization of deceased donor tissue with results approximating those of living donor tissue transplanted for severe bilateral LSCD.

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关键词

Keratolimbal allograft,KLAL,Cadaver,Deceased donor,HLA,ABO blood type,Compatible,Matching,Limbal stem cell deficiency,Limbal stem cell transplant,Ocular surface stem cell transplant

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