Hydrophilic platinum(II) complexes containing 5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidine: Spectroscopic and in vitro cytotoxic characterization

Four platinum(II) complexes containing 5,7-methyl-1,2,4-triazolo[1,5-a]pyrimidine(dmtp) of the general formula cis-[Pt(X)2(dmtp)2], where X – acetato (1), trichloroacetato (2), trifluoroacetato (3), nitrato (4) have been isolated and characterized by spectroscopical methods 1H, 13C, 15N, 195Pt NMR and IR). Hydrophilic platinum(II) complexes (1–4), revealed rather moderate in vitro cytotoxicity.